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Review Article Volume 3 Issue 1
Abstract: Crohn's disease (CD) and ulcerative colitis (UC), the constituents of Inflammatory Bowel Disease (IBD), are the most
destructive benign diseases of young adults. Two-hundred thousand young men and women in North America will have
major bowel resection annually, half to experience a premature death and many an increased risk of colorectal cancer.
New cases in the youngest quadrille are appearing at a 0.5 percent rate per year. Adalimumab, the last pharmaceutical
TNF-inhibitor drug approved for IBD was 17 years ago.
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Original Article Volume 3 Issue 1
Abstract: Endoscopic biopsy results and abdominal CT findings of patients admitted at the endoscopy unit of Gastroenterology Department between September 2008 and December 2014 with a working diagnosis of gastric carcinoma were retrospectively compared.
Research Article Volume 2 Issue 1
Abstract: Celiac disease is an autoimmune disorder that occurs in genetically predisposed people in which the ingestion of gluten leads to a damage in the small intestine that clinically presents with malabsorption related symptoms. However it is known that celiac disease can also be the underlying cause of several non-gastrointestinal symptoms. This review summarizes the studies and data acquired on the relationship between celiac disease and gynecological/obstetric disorders. Over the past few decades numerous studies highlighted the existence of a linkage between celiac disease and gynecological/obstetric disorders such as delayed menarche, early menopause, amenorrhea or infertility and adverse pregnancy outcomes.
Clinical Image Volume 2 Issue 1
Abstract: A 29-year-old female with a history of bipolar disorder presented to the emergency department (ED) with worsening epigastric pain. Two years ago, esophagogastroduodenoscopy (EGD) showed a 1.5-cm benign-appearing superficial ulcer in the pylorus. She was presumed to have an NSAID-induced peptic ulcer and was treated with proton pump inhibitor therapy. She had multiple hospitalizations for abdominal pain and several subsequent EGDs showing refractory gastric ulcer.
Original Article Volume 2 Issue 1
Abstract: The incidence of inflammatory bowel diseases (IBD), including Crohn disease (CD) and ulcerative colitis (UC), is increasing in children. We recently demonstrated increased epithelial gaps in the non-inflamed duodenum of CD and UC patients, and high capillary flow rates in the duodenum of UC patients using probe-based confocal laser endomicroscopy (pCLE). The aim of the present study was to determine if increased epithelial gap density or capillary flow could predict the clinical course of IBD patients and response to therapy.
Case Report Volume 1 Issue 2
Abstract: Pill-induced esophageal injury was first described in 1970. It occurs when a caustic medicinal pill dissolves in the esophagus and releases its noxious content, particularly if transit is delayed. Injury of this type, called pill esophagitis or pill induced esophageal injury is common but unfortunately is under-reported.
Original Article Volume 1 Issue 2
Abstract: Bile duct injury management requires skill of experienced surgeons at referral centers. Multiple factors may alter their outcomes.
Abstract: Recent epidemiological data demonstrate a rise in the prevalence of Hepatocellular Carcinoma (HCC) and Non-Alcoholic Fatty Liver Disease (NAFLD) in obesity and diabetes.
Original Research Volume 1 Issue 2
Abstract: As Human Gastric Cancer Death Rates (HGCDR) is unevenly distributed in western Venezuela, we explored possible risk factors, among which Helicobacter Pylori (Hp) infection alongside bracken fern invasion could be differential contributors.
Prospective Volume 1 Issue 2
Abstract: It is widely understood that art expresses human experience to an audience. The viewer is provided with a unique form of insight when art is created by individuals depicting their own disease.
Case Report Volume 1 Issue 1
Abstract: Tumor lysis syndrome in hematological malignancy is more common than in solid tumors. Little literature has been published on tumor lysis syndrome in solid tumors.
Clinical Image Volume 1 Issue 1
Abstract: A 56-year-old Japanese woman with no notable medical history was admitted to our clinic because of abnormal changes in upper gastrointestinal series for regular checkup. An upper gastrointestinal endoscopy was performed. In the duodenum, white plaques resembling lymphoid hyperplasia were detected (Figure 1A, arrowheads).
Abstract: Codeine is a rare precipitant of acute pancreatitis. The hypothesised mechanism is transient codeine-induced sphincter of Oddi spasm. This case report describes an 80-year-old woman with previous cholecystectomy who developed acute pancreatitis within one hour after administration of a low dose (60 mg) codeine phosphate preparation for sialadenitis.
Review Article Volume 1 Issue 1
Abstract: Histamine is a biogenic amine originating endogenously or exogenously from Histidine by enzymatic decarboxylation. Endogenous histamine is mostly generated by basophils and mast cells that, when activated, will release histamine that is involved in various regulatory processes but also will induce multiple allergic effects (hypotension, tachycardia, vascular risks) including anaphylactic shock and possible death.
Abstract: The proband was of Arabic descent and evaluated for intractable diarrhea and poor growth. Molecular testing identified a nonsense mutation in the sucrase-isomaltase (SI) gene consistent with a diagnosis of sucrase-isomaltase deficiency (CSID).
Abstract: The future consequences of climate change and its impact on food safety is still not clear due to many variations and uncertanities. It is obvious that seasonal distribution and incidence of campylobacteriosis, salmonellosis and vero-toxigenic Escherichia coli borne diseases are increasing as the environmental temperature increases.
Research Article Volume 1 Issue 1
Abstract: Verotoxigenic Escherichia coli renamed after detection of production ability of cytotoxin which kills Vero cells, a continuous cell line derived from the kidney of the African green monkey (Chlorocebus sp). These toxins are proved to cause severe diseases in humans.
Abstract: Gastrointestinal stromal tumors (GIST) are the most common mesenchymal neoplasms of the digestive tract. A small percentage of GISTs form extragastrointestinal masses in the omentum, mesenteries, retroperitoneum, and undefined abdominal sites. These tumors have been labelled as "extra-gastrointestinal stromal tumors" (EGISTs). By definition, extragastrointestinal stromal tumors display no connection to the walls of the gastrointestinal tubular organs.
Abstract: To study the prevalence of gastrointestinal disorders, understand the compliance to treatment among Iraqi Arabs and Iraqi Chaldeans, and predict risk factors for gastrointestinal disorders. 350 random samples of Iraqi Americans, who immigrated to United States from Iraq at different times reported gastrointestinal disorders. Compliance to treatment was evaluated.